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Mouse Complement C1q tumor necrosis factor-related protein 6(C1QTNF6) ELISA kit

  • 中文名稱:
    小鼠補體C1q腫瘤壞死因子相關蛋白6(C1QTNF6)酶聯免疫試劑盒
  • 貨號:
    CSB-EL003651MO
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    小鼠補體C1q腫瘤壞死因子相關蛋白6(C1QTNF6)酶聯免疫試劑盒(CSB-EL003651MO)檢測樣本中的C1QTNF6含量。C1QTNF6是一種與炎癥和代謝相關的基因,其表達與多種疾病如1型糖尿病、多囊卵巢綜合征等密切相關。研究顯示,C1QTNF6在相關疾病中的表達異常可能通過調節炎癥反應和代謝途徑影響疾病進程。該產品適用于基礎科研中探索C1QTNF6在代謝性疾病、慢性炎癥或癌癥發生發展中的作用機制,亦可用于評估藥物干預或基因編輯模型下靶蛋白的調控效果。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    C1qtnf6Complement C1q tumor necrosis factor-related protein 6 ELISA Kit
  • 縮寫:
    C1QTNF6
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum,plasma, tissue homogenates
  • 檢測范圍:
    31.25 pg/ml-2000 pg/ml
  • 靈敏度:
    7.81pg/ml
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Others
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. The results establish CTRP6 as a novel metabolic/immune regulator linking obesity to adipose tissue inflammation and insulin resistance. PMID: 28726640
    2. CTRP6 knockdown down-regulated the levels of lipogenic genes and phosphorylated Erk1/2 (p-Erk1/2) in the early lipogenic stage, whereas up-regulated p-Erk1/2 in the terminal differentiation in skeletal myoblasts. PMID: 27125977
    3. CTRP6 specifically suppresses the alternative pathway of the complement system. C1qtnf6(-/-) mice are highly susceptible to induced arthritis, Arthus reaction, and experimental autoimmune encephalomyelitis. PMID: 26404464
    4. Knockdown of CTRP6 can inhibit adipogenesis of 3T3-L1 adipocytes through lipogenic marker genes and Erk1/2 signaling pathway. PMID: 25639984
    5. CTRP6 plays a role in fatty acid metabolism via the AMPK-ACC pathway. The globular domain of CTRP6 mediates the phosphorylation and activation of the 5'-AMP-activated protein kinase (AMPK) in skeletal muscle cells. PMID: 20102710

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  • 亞細胞定位:
    Secreted.
  • 數據庫鏈接:


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