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Mouse Carbonic anhydrase 3(CA3) ELISA kit

  • 中文名稱:
    小鼠碳酸酐酶3(CA3)酶聯免疫試劑盒
  • 貨號:
    CSB-EL004371MO
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    小鼠碳酸酐酶3(CA3)酶聯免疫試劑盒(CSB-EL004371MO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的CA3含量。當前所給信息中未包含 CA3 的背景及研究機制相關內容,無法按要求進行總結。若能補充 CA3 在醫學、生物學等領域的背景情況及研究機制方面信息,即可完成總結。試劑盒檢測范圍為4.69 pg/mL-300 pg/mL,適用于基礎科研中探索CA3在肌肉代謝、能量穩態調節或疾病模型中的動態表達。為細胞實驗、動物模型研究及生物標志物篩選提供可靠工具,尤其適用于運動生理學、代謝紊亂機制或相關基因功能研究等領域的定量分析需求。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Ca3 ELISA Kit; Car3Carbonic anhydrase 3 ELISA Kit; EC 4.2.1.1 ELISA Kit; Carbonate dehydratase III ELISA Kit; Carbonic anhydrase III ELISA Kit; CA-III ELISA Kit
  • 縮寫:
    CA3
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    4.69 pg/mL-300 pg/mL
  • 靈敏度:
    1.17 ng/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Cell Biology
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Reversible hydration of carbon dioxide.
  • 基因功能參考文獻:
    1. CAIII is highly expressed in osteocytes, is regulated by parathyroid hormone both in vitro and in vivo, and protects osteocytes from oxidative stress. PMID: 28928248
    2. Our results indicate that Car3 is not required for de novo lipogenesis, and Car3 knockout mice fed high-fat diet do not have significant differences in responses to various diets to wild type mice. PMID: 28437447
    3. The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. PMID: 25684186
    4. We conclude that down-regulation of CAIII in preadipocytes enhances adipogenesis and that CAIII is a regulator of adipogenic differentiation which acts at the level of PPAR-gamma2 gene expression. PMID: 22507175
    5. Mice lacking carbonic anhydrase III were viable and fertile and had normal life spans. PMID: 15509796
    6. lack of proximal tubule cLCN5 in mice and men is associated with CAIII induction, increased cell proliferation, and oxidative stress PMID: 18322545

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  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    Alpha-carbonic anhydrase family
  • 組織特異性:
    Expressed at lower levels in adipose tissue from animals that were either genetically obese or had experimentally induced obesity.
  • 數據庫鏈接:

    KEGG: mmu:12350

    STRING: 10090.ENSMUSP00000029076

    UniGene: Mm.300