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Mouse C-X-C motif chemokine 3(CXCL3) ELISA kit

  • 中文名稱:
    小鼠C-X-C趨化因子3(CXCL3)酶聯免疫試劑盒
  • 貨號:
    CSB-EL006249MO
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    小鼠C-X-C趨化因子3(CXCL3)酶聯免疫試劑盒(CSB-EL006249MO)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的CXCL3含量。CXCL3作為一個靶點,其屬于趨化因子家族。背景上在炎癥等生理病理過程中發揮作用。研究機制方面,它能與相應受體結合,介導細胞遷移和活化,參與免疫反應調節,在腫瘤、自身免疫病等發病機制研究中有重要意義。試劑盒檢測范圍為7.8 pg/mL-500 pg/mL,適用于基礎科研領域,例如通過分析CXCL3在小鼠感染模型、自身免疫性疾病模型或腫瘤移植模型中的動態變化,探究其與中性粒細胞募集、血管生成或免疫逃逸等過程的關聯機制。支持科研人員高效開展CXCL3相關分子機制研究及生物標志物探索。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Cxcl3 ELISA Kit; Dcip1 ELISA Kit; Gm1960C-X-C motif chemokine 3 ELISA Kit; Dendritic cell inflammatory protein 1 ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Mus musculus (Mouse)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    7.8 pg/mL-500 pg/mL
  • 靈敏度:
    1.56 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Immunology
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:

  • 線性度:

  • 回收率:

  • 標準曲線:

  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
  • 基因功能參考文獻:
    1. The studies revealed that, although overall structural and oligomerization features of CXCL3 and CXCL2 are similar, prominent differences were observed in their surface characteristics, thus implicating a functional divergence. PMID: 28928065
    2. these results have indicated that CXCL3 is a novel adipokine that facilitates adipogenesis in an autocrine and/or a paracrine manner through induction of c/ebpb and c/ebpd. PMID: 27512010
    3. Tis21 induces migration of cerebellar granule neuron precursor cells through Cxcl3, which may represent a novel target for medulloblastoma therapy PMID: 23115191
    4. DCIP-1 interacts with chemokine CXCR2 and mediates human neutrophil chemotaxis, consistent with its role during the early proinflammatory phase of dendritic cell maturation. PMID: 14764687
  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 數據庫鏈接:


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