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  4. Human Pregnancy-specific beta-1-glycoprotein 9(PSG9) ELISA kit

Human Pregnancy-specific beta-1-glycoprotein 9(PSG9) ELISA kit

  • 中文名稱：
    人妊娠特異性β1糖蛋白9(PSG9)酶聯(lián)免疫試劑盒
  • 貨號：
    CSB-EL018859HU
  • 規(guī)格：
    96T/48T
  • 價格：
    ￥3600/￥2500
  • 促銷：
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人妊娠特異性β1糖蛋白9(PSG9)酶聯(lián)免疫試劑盒（CSB-EL018859HU）為雙抗夾心法ELISA試劑盒，定量檢測血清、血漿樣本中的PSG9含量。人妊娠特異性β1糖蛋白9（PSG9）是一種由胎盤合體滋養(yǎng)層細胞合成的妊娠特異性糖蛋白，參與母胎界面免疫調(diào)節(jié)及胚胎發(fā)育。研究發(fā)現(xiàn)PSG9在子癇前期患者中表達下調(diào)，可能成為預測子癇前期的潛在生物標志物。試劑盒檢測范圍為5 μg/mL-150 μg/mL，適用于妊娠相關(guān)疾病的機制研究、胎盤功能評估及腫瘤生物學等科研領(lǐng)域；為生殖醫(yī)學、腫瘤微環(huán)境等基礎(chǔ)研究提供可靠工具本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見產(chǎn)品說明書。
  • 別名：
    pregnancy specific beta 1 glycoprotein (PSG) ELISA Kit; pregnancy specific beta 1 glycoprotein 11 ELISA Kit; pregnancy specific beta 1 glycoprotein 9 ELISA Kit; pregnancy specific beta 1 glycoprotein B ELISA Kit; Pregnancy-specific beta-1 glycoprotein B ELISA Kit; Pregnancy-specific beta-1-glycoprotein 11 ELISA Kit; Pregnancy-specific beta-1-glycoprotein 9 ELISA Kit; Pregnancy-specific glycoprotein 11 ELISA Kit; Pregnancy-specific glycoprotein 7 ELISA Kit; Pregnancy-specific glycoprotein 9 ELISA Kit; PS beta B ELISA Kit; PS-beta-B ELISA Kit; PS-beta-G-11 ELISA Kit; PS-beta-G-9 ELISA Kit; PS34 ELISA Kit; PSBG 9 ELISA Kit; PSBG-11 ELISA Kit; PSBG-9 ELISA Kit; PSG 9 ELISA Kit; PSG11 ELISA Kit; PSG7 ELISA Kit; PSG9 ELISA Kit; PSG9_HUMAN ELISA Kit; PSGII ELISA Kit
  • 縮寫：
    PSG9
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma
  • 檢測范圍：
    5 μg/mL-150 μg/mL
  • 靈敏度：
    1.25 μg/mL
  • 反應(yīng)時間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測波長：
    450 nm
  • 研究領(lǐng)域：
    Tags & Cell Markers
  • 測定原理：
    quantitative
  • 測定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<15%        
    Three samples of known concentration were tested twenty times on one plate to assess.    
    Inter-assay Precision (Precision between assays): CV%<15%        
    Three samples of known concentration were tested in twenty assays to assess.      
                   
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human PSG9 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.  
    　 Sample Serum(n=4)    
    1:1 Average % 95    
    Range % 91-99    
    1:2 Average % 89    
    Range % 83-99    
    1:4 Average % 98    
    Range % 90-105    
    1:8 Average % 92    
    Range % 88-100    
  • 回收率：
    The recovery of human PSG9 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.  
     
    Sample Type Average % Recovery Range    
    Serum (n=5) 97 93-100    
    EDTA plasma (n=4) 96 91-99    
                   
                   
  • 標準曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.  
     
    μg/ml OD1 OD2 Average Corrected    
    150 2.523 2.514 2.519 2.471    
    62.5 1.308 1.317 1.313 1.265    
    25 0.624 0.609 0.617 0.569    
    10 0.316 0.305 0.311 0.263    
    5 0.156 0.152 0.154 0.106    
    0 0.047 0.048 0.048 　    
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評價

靶點詳情

  • 基因功能參考文獻：
    1. Results indicate that pregnancy-specific glycoprotein 9 (PSG9) may facilitate the development of hepatocellular carcinoma (HCC) by fostering angiogenesis via promoting VEGFA production in cancer HCC. PMID: 28078509
    2. Findings illustrate the innovative mechanism by which PSG9 drives the progression of colorectal cancer and tumor angiogenesis. This occurs via nuclear translocation of PSG9/SMAD4, which activates angiogenic cytokines. PMID: 27528036
    3. PSG9, through its activation of TGFbeta-1, could be a potent inducer of immune tolerance PMID: 27389696
    4. PSG9 may have a role in development of colorectal carcinogenesis in patients with adenomatous polyposis coli PMID: 15982419
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    Immunoglobulin superfamily, CEA family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9526

    OMIM: 176398

    KEGG: hsa:5678

    STRING: 9606.ENSP00000270077

    UniGene: Hs.502092



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