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Human Myeloid-derived growth factor(MYDGF) ELISA kit

  • 中文名稱:
    人骨髓衍生生長因子 (MYDGF)酶聯免疫試劑盒
  • 貨號:
    CSB-EL003433HU
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    人骨髓衍生生長因子 (MYDGF)酶聯免疫試劑盒(CSB-EL003433HU)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的MYDGF含量。MYDGF 即中腦星形膠質細胞衍生神經營養因子,一般在心臟中發揮調控能量代謝、保護心肌等作用。試劑盒檢測范圍為0.156 ng/mL-10 ng/mL,適用于心血管疾病機制研究、代謝調控通路探索、抗炎藥物開發等科研場景中生物標志物表達水平的動態監測,亦可用于評估疾病模型動物或細胞實驗中MYDGF的調控效果。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    C19orf10 ELISA Kit; Chromosome 19 open reading frame 10 ELISA Kit; CS010_HUMAN ELISA Kit; EUROIMAGE1875335 ELISA Kit; IL 25 ELISA Kit; IL 27 ELISA Kit; IL-25 ELISA Kit; IL25 ELISA Kit; IL27 ELISA Kit; IL27w ELISA Kit; Interleukin 25 ELISA Kit; Interleukin 27 working designation ELISA Kit; Interleukin-25 ELISA Kit; Interleukin25 ELISA Kit; R33729 1 ELISA Kit; R337291 ELISA Kit; SF20 ELISA Kit; Stromal cell derived growth factor ELISA Kit; Stromal cell derived growth factor SF20 ELISA Kit; Stromal cell-derived growth factor SF20 ELISA Kit; Uncharacterized protein C19orf10 precursor ELISA Kit; UPF0556 protein C19orf10 ELISA Kit
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    0.156 ng/mL-10 ng/mL
  • 靈敏度:
    0.039 ng/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Cardiovascular
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    Bone marrow-derived monocyte and paracrine-acting protein that promotes cardiac myocyte survival and adaptive angiogenesis for cardiac protection and/or repair after myocardial infarction (MI). Stimulates endothelial cell proliferation through a MAPK1/3-, STAT3- and CCND1-mediated signaling pathway. Inhibits cardiac myocyte apoptosis in a PI3K/AKT-dependent signaling pathway. Involved in endothelial cell proliferation and angiogenesis.
  • 基因功能參考文獻:
    1. Bone marrow-derived monocytes and macrophages produce this protein endogenously to protect and repair the heart after myocardial infarction. PMID: 25581518
    2. Taken together, these data suggest that c19orf10 might be one of the growth factors and potential molecular targets activated in HCC. PMID: 21128247
    3. we identified a novel protein, c19orf10 (chromosome 19 open reading frame 10), produced by fibroblast-like synoviocytes PMID: 17362502
  • 亞細胞定位:
    Secreted. Endoplasmic reticulum-Golgi intermediate compartment. Endoplasmic reticulum. Golgi apparatus.
  • 蛋白家族:
    MYDGF family
  • 組織特異性:
    Expressed in eosinophils (at protein level). Expressed in bone marrow cells. Expressed in synovial tissue. Found in synovial fluid of patients with arthropaties.
  • 數據庫鏈接:

    HGNC: 16948

    OMIM: 606746

    KEGG: hsa:56005

    STRING: 9606.ENSP00000262947

    UniGene: Hs.465645