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Human Long palate, lung and nasal epithelium carcinoma-associated protein 4(C20orf186) ELISA kit

  • 中文名稱:
    人腭/肺/鼻上皮癌關聯蛋白4(C20orf186)酶聯免疫試劑盒
  • 貨號:
    CSB-EL003694HU
  • 規格:
    96T/48T
  • 價格:
    ¥3600/¥2500
  • 促銷:
  • 其他:

產品詳情

  • 產品描述:
    人腭/肺/鼻上皮癌關聯蛋白4(C20orf186)酶聯免疫試劑盒(CSB-EL003694HU)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的C20orf186含量。試劑盒檢測范圍為25 pg/mL-1600 pg/mL,該產品可應用于基礎科研領域,如探究C20orf186在鼻咽癌、肺癌等上皮源性腫瘤中的表達特征,評估其作為潛在生物標志物的相關性,或用于藥物干預實驗中靶蛋白水平變化的動態監測,為腫瘤發生機制研究及治療策略開發提供實驗支持。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    BPI fold-containing family B member 4 ELISA Kit; Bpifb4 ELISA Kit; C20orf186 ELISA Kit; dJ726C3.5 ELISA Kit; Gm1006 ELISA Kit; Ligand-binding protein RY2G5 ELISA Kit; Long palate; lung and nasal epithelium carcinoma-associated protein 4 ELISA Kit; LPLC4_HUMAN ELISA Kit; Lplunc4 ELISA Kit
  • 縮寫:
    C20orf186
  • Uniprot No.:
  • 種屬:
    Homo sapiens (Human)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    25 pg/mL-1600 pg/mL
  • 靈敏度:
    6.25 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Neuroscience
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of human C20orf186 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
    SampleSerum(n=4)
    1:1Average %93
    Range %86-97
    1:2Average %98
    Range %92-106
    1:4Average %84
    Range %81-89
    1:8Average %91
    Range %83-98
  • 回收率:
    The recovery of human C20orf186 spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 10196-105
    EDTA plasma (n=4)9388-99
  • 標準曲線:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    16002.908 3.158 3.033 2.897
    8002.304 2.433 2.369 2.233
    4001.478 1.475 1.477 1.341
    2000.686 0.707 0.697 0.561
    1000.497 0.503 0.500 0.364
    500.263 0.277 0.270 0.134
    250.230 0.244 0.237 0.101
    00.140 0.132 0.136
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

靶點詳情

  • 功能:
    May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received.
  • 基因功能參考文獻:
    1. LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanism. PMID: 28419216
    2. In conclusion, BPIFB4 and CXCR4 expression classify long-lived individuals health status that correlates with maintained mononuclear cell migration. PMID: 28121621
    3. Longevity-associated variant-BPIFB4 may represent a novel therapeutic tool to fight endothelial dysfunction and promote vascular reparative processes. PMID: 26034043
  • 亞細胞定位:
    Secreted. Cytoplasm.
  • 蛋白家族:
    BPI/LBP/Plunc superfamily, BPI/LBP family
  • 組織特異性:
    Expressed in nasal tissue.
  • 數據庫鏈接:

    HGNC: 16179

    OMIM: 615718

    KEGG: hsa:149954

    STRING: 9606.ENSP00000364632

    UniGene: Hs.38961