国产午夜福利片1000无码丨人妻国产成人久久av免费高清丨午夜做受视频试看6次丨日韩av不卡一区在线免费观看丨在线观看精品三级欧美

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 試劑盒
  3. 酶聯(lián)免疫試劑盒
  4. Human Bone morphogenetic protein 8B(BMP8B) ELISA kit

Human Bone morphogenetic protein 8B(BMP8B) ELISA kit

  • 中文名稱：
    人骨形態(tài)發(fā)生蛋白8B(BMP8B)酶聯(lián)免疫試劑盒
  • 貨號(hào)：
    CSB-EL002746HU
  • 規(guī)格：
    96T/48T
  • 價(jià)格：
    ￥3600/￥2500
  • 促銷：
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    人骨形態(tài)發(fā)生蛋白8B(BMP8B)酶聯(lián)免疫試劑盒（CSB-EL002746HU）為雙抗夾心法ELISA試劑盒，定量檢測(cè)血清、血漿、組織勻漿樣本中的BMP8B含量。BMP8B屬于骨形態(tài)發(fā)生蛋白家族成員。在背景上，它參與多種生理進(jìn)程。研究機(jī)制方面，其能調(diào)控細(xì)胞的增殖、分化和凋亡等，在骨代謝、生殖系統(tǒng)等方面發(fā)揮作用，深入研究它對(duì)理解相關(guān)生理病理過(guò)程有重要意義。試劑盒檢測(cè)范圍為9.37 pg/mL-600 pg/mL，該產(chǎn)品適用于體外研究BMP8B在骨代謝調(diào)控機(jī)制、生殖系統(tǒng)功能分析或特定病理模型（如骨發(fā)育異常、組織纖維化等）中的動(dòng)態(tài)表達(dá)特征，為探索其分子作用機(jī)制提供可靠工具。實(shí)驗(yàn)操作流程簡(jiǎn)便，兼容常規(guī)實(shí)驗(yàn)室設(shè)備，支持多樣本類型分析，尤其適用于需要高靈敏度檢測(cè)的細(xì)胞或動(dòng)物模型研究。本品僅用于科研，不用于臨床診斷，產(chǎn)品具體參數(shù)及操作步驟詳見(jiàn)產(chǎn)品說(shuō)明書。
  • 別名：
    BMP-8 ELISA Kit; BMP-8B ELISA Kit; BMP8 ELISA Kit; Bmp8b ELISA Kit; BMP8B_HUMAN ELISA Kit; bone morphogenetic protein 8 (osteogenic protein 2) ELISA Kit; Bone morphogenetic protein 8 ELISA Kit; Bone morphogenetic protein 8B ELISA Kit; dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2)) ELISA Kit; OP-2 ELISA Kit; OP2 ELISA Kit; Osteogenic protein 2 ELISA Kit
  • 縮寫：
  • Uniprot No.：
  • 種屬：
    Homo sapiens (Human)
  • 樣本類型：
    serum, plasma, tissue homogenates
  • 檢測(cè)范圍：
    9.37 pg/mL-600 pg/mL
  • 靈敏度：
    2.34 pg/mL
  • 反應(yīng)時(shí)間：
    1-5h
  • 樣本體積：
    50-100ul
  • 檢測(cè)波長(zhǎng)：
    450 nm
  • 研究領(lǐng)域：
    Signal Transduction
  • 測(cè)定原理：
    quantitative
  • 測(cè)定方法：
    Sandwich
  • 精密度：
    Intra-assay Precision (Precision within an assay): CV%<8%      
    Three samples of known concentration were tested twenty times on one plate to assess.  
    Inter-assay Precision (Precision between assays): CV%<10%      
    Three samples of known concentration were tested in twenty assays to assess.    
                 
  • 線性度：
    To assess the linearity of the assay, samples were spiked with high concentrations of human BMP8B in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
      Sample Serum(n=4)  
    1:5 Average % 94  
    Range % 90-98  
    1:10 Average % 88  
    Range % 82-94  
    1:20 Average % 103  
    Range % 99-108  
    1:40 Average % 95  
    Range % 90-100  
  • 回收率：
    The recovery of human BMP8B spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample Type Average % Recovery Range  
    Serum (n=5) 96 92-100  
    EDTA plasma (n=4) 98 94-103  
                 
                 
  • 標(biāo)準(zhǔn)曲線：
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/ml OD1 OD2 Average Corrected  
    600 2.056 2.205 2.131 2.008  
    300 1.607 1.724 1.666 1.543  
    150 1.102 1.075 1.089 0.966  
    75 0.645 0.603 0.624 0.501  
    37.5 0.394 0.373 0.384 0.261  
    18.75 0.291 0.302 0.297 0.174  
    9.37 0.187 0.201 0.194 0.071  
    0 0.120 0.125 0.123    
  • 數(shù)據(jù)處理：
  • 貨期：
    3-5 working days

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
  • 基因功能參考文獻(xiàn)：
    1. Acetylated H3K9 and H4K16 levels at BMP8B were increased in gastric cancer (GC) compared to nontumors (P < 0.05). However, reduced levels of acetylated H3K9 and H4K16 were associated with poorly differentiated GC (P < 0.05). PMID: 27748538
    2. Study found that BMP8B was downregulated in pancreatic cancer tissues and BMP8B mediates the survival of pancreatic cancer cells and regulates the progression of pancreatic cancer. PMID: 25176058
    3. Five novel SNPs within BMP8B gene.Genetic variants in BMP8B gene are associated with growth traits in Chinese native cattle. PMID: 24076131
    4. Epigenetic silencing of the bone morphogenetic protein 2 gene through methylation is associated with gastric carcinomas PMID: 16314833
    5. Reports on the mouse homolog of this gene. PMID: 9070944

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 蛋白家族：
    TGF-beta family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 1075

    OMIM: 602284

    KEGG: hsa:656

    STRING: 9606.ENSP00000361915

    UniGene: Hs.734367



主站蜘蛛池模板： 景洪市| 永春县| 鄄城县| 南阳市| 宕昌县| 汉源县| 车险| 安国市| 上栗县| 公主岭市| 肥乡县| 广汉市| 惠东县| 炉霍县| 封丘县| 隆子县| 东台市| 吉木萨尔县| 定襄县| 鱼台县| 同心县| 河池市| 旌德县| 巴楚县| 昭苏县| 宁国市| 临泽县| 灌南县| 特克斯县| 宁海县| 罗田县| 察哈| 贞丰县| 慈溪市| 淮南市| 黑河市| 调兵山市| 泸西县| 峨眉山市| 马龙县| 霍山县|