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  4. Recombinant Human Dipeptidase 1 (DPEP1)

Recombinant Human Dipeptidase 1 (DPEP1)

  • 貨號(hào)：
    007123HU
  • 產(chǎn)品類型：
    Recombinant Proteins
  • 規(guī)格：
  • Uniprot No.：
  • 別名：
    Dehydropeptidase-I; Dipeptidase 1 (renal); Dipeptidase 1; DPEP1; DPEP1_HUMAN; hRDP; MBD1; MDP; Microsomal dipeptidase; RDP; Renal dipeptidase
  • 序列：

    DFFR DEAERIMRDS PVIDGHNDLP WQLLDMFNNR LQDERANLTT LAGTHTNIPK LRAGFVGGQF WSVYTPCDTQ NKDAVRRTLE QMDVVHRMCR MYPETFLYVT SSAGIRQAFR EGKVASLIGV EGGHSIDSSL GVLRALYQLG MRYLTLTHSC NTPWADNWLV DTGDSEPQSQ GLSPFGQRVV KELNRLGVLI DLAHVSVATM KATLQLSRAP VIFSHSSAYS VCASRRNVPD DVLRLVKQTD SLVMVNFYNN YISCTNKANL SQVADHLDHI KEVAGARAVG FGGDFDGVPR VPEGLEDVSK YPDLIAELLR RNWTEAEVKG ALADNLLRVF EAVEQASNLT QAPEEEPIPL DQLGGSCRTH YGYSS

  • 其他：
  • 功能：
    Hydrolyzes a wide range of dipeptides including the conversion of leukotriene D4 to leukotriene E4. Hydrolyzes cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation. Possesses also beta lactamase activity and hydrolytically inactivates beta-lactam antibiotics.; Independently of its dipeptidase activity acts as an adhesion receptor for neutrophils recruitement from bloodstream into inflammed lungs and liver.
  • 亞細(xì)胞定位：
    Apical cell membrane; Lipid-anchor, GPI-anchor. Cell projection, microvillus membrane; Lipid-anchor, GPI-anchor.
  • 蛋白質(zhì)家族：
    Metallo-dependent hydrolases superfamily, Peptidase M19 family
  • 組織特異性：
    Expressed in lung and kidneys.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 3002

    OMIM: 179780

    KEGG: hsa:1800

    STRING: 9606.ENSP00000261615

    UniGene: Hs.109