Recombinant Rat C-X-C motif chemokine 3 protein (Cxcl3)

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產品詳情

純度：

>96% as determined by SDS-PAGE.
內毒素：

Less than 1.0 EU/μg as determined by LAL method.
生物活性：

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human CXCR2 transfected murine BaF3 cells is in a concentration range of 5-50 ng/ml.
基因名：

Cxcl3
Uniprot No.：

Q10746
別名：

Cxcl3; Cinc2C-X-C motif chemokine 3; Cytokine-induced neutrophil chemoattractant 2; CINC-2; Macrophage inflammatory protein 2-alpha/beta; MIP2-alpha/beta
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
來源：

E.Coli
分子量：

7.8 kDa
表達區域：

33-101aa
氨基酸序列

RELRCQCLKT LPRVDFENIQ SLTVTPPGPH CTQTEVIATL KDGQEVCLNP QAPRLQKIIQ KLLKSDKSS
蛋白標簽：

Tag-Free
產品提供形式：

Liquid or Lyophilized powder
緩沖液：

0.2 ?m filtered 20 mM PB, pH 7.4, 50 mM NaCl,lyophilized
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

5-10 business days
Datasheet & COA：

Please contact us to get it.

功能：

Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion.
基因功能參考文獻：
1. this study shows elevated expression of CINC-2 at the site of inflammation as well as their significant reflection in the circulation, thereby suggesting their frontline role in carrageenan-induced acute inflammation PMID: 27967265
2. CINC-2beta is regulated differently from most other chemokines and that its expression is related to the state of alveolar type II cell differentiation. PMID: 16055671
亞細胞定位：

Secreted.
蛋白家族：

Intercrine alpha (chemokine CxC) family
數據庫鏈接：

KEGG: rno:171551

STRING: 10116.ENSRNOP00000038520

UniGene: Rn.10525